An article by Dr. So Nakagawa was published in Daily Gendai on April 21.  “What is the difference between the new coronavirus and the 9% lethal SARS?”

Apr.21, 2020

Picture is cited from Daily Gendai 2020

Picture is cited from Daily Gendai 2020


Many people think of the new coronavirus as “a little heavy flu,” but it’s a mistake. In fact, it is the same coronavirus as the “Severe Acute Respiratory Syndrome (SARS) virus” with a fatality rate of 9.6%, and the genes are also very similar. How long? Interview with Dr. So Nakagawa, Ph.D., who is a postdoctoral researcher at the National Institute of Genetics, a visiting researcher at Harvard University, and a lecturer at the Molecular Life Sciences School of Medicine, Tokai University.

“The similarity of the genes that make up each virus is about 70 to 90%. However, the new coronavirus is not an evolution of the SARS virus. They are like relatives. One of the genes with the lowest similarity compared to each other is the S gene. ” The spike protein (S protein) forming the viral protrusion has the role of binding to the receptor on the surface of the infected cell and mediating the fusion of the viral outer membrane and cell membrane. The S gene has a design drawing that determines the character of the S protein and creates it faithfully.

(Continued to the Daily Gendai official website)

Comparative Virology and Genomic Analysis of the New Coronavirus

Apr. 28, 2020

Undergraduate School of Medicine, Department of Molecular Life Sciences, Basic Medical Science and Molecular Medicine Junior Associate Professor So Nakagawa (The Institute of Medical Sciences and Micro/Nano Technology Center) and Associate Professor Takayuki Miyazawa of the Institute for Frontier Life and Medical Sciences, Kyoto University published a special feature in the May edition of Jikken Igaku (Yodosha).

The article, titled “Comparative Virology and Comparative Genomic Analysis of the Novel Coronavirus SARS-CoV-2,” was also included in the online version of the publication. Nakagawa is an expert in genomics and bioinformatics whose research focuses on the coevolution on viruses and their hosts. The article was submitted after a request from the publishing company. It analyzes the new coronavirus SARS-CoV-2 from the view of comparative virology and genomics, building off of the published research of many other scientists. The article describes the virological classification and properties of SARS-CoV-2, its genomic structure, and spontaneous mutations.

See the full text

*The online version of the article published in Jikken Igaku is available at the website below (Japanese only).
(You must register for a free Yodosha HP membership to view the article.)

Picture is cited from Tokai website 2020

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